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Inhibition of sterol 4-methyl oxidase is the principal mechanism by which garlic decreases cholesterol synthesis

Although the etiology of IBD remains unclear, it is generally considered to be the result of a confluence of environmental factors (such as nutrition and microbiota), immune system dysregulation, intestinal epithelial barrier impairment, and genetic predisposition (178)

Still, they do not answer how cancer behaves in the hosts natural environment